The two victims, whose ages were not immediately known, were shot about 6 p.m. on westbound I-290 near South California, according to preliminary information from Illinois State Police.
The Cook County medical examiner’s office could not immediately confirm the fatality early Thursday.
They were both taken to Stroger Hospital, but the female’s condition was not immediately available, police said.
Police said they will be closing down all westbound I-290 lanes about 7:30 a.m. to search for shell casings.
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